UW-Madison’s Research Challenge

I’m late in posting the stories I’ve written for Isthmus on UW-Madison’s struggles as a great research university to get its inventions and discoveries into the broader world.  Here’s how the first story begins:

It’s a story that Madison loves to hear.

Two plucky entrepreneurs, Kevin Conroy and Manesh Arora, are hired in 2009 to revive a moribund health-tech startup in Boston. They have the temerity to move it from the best-known metropolis in the country for medical innovation to the much smaller Madison, where Conroy had run Third Wave Technologies. Their company had but two employees.

“Without the UW-Madison, Exact Sciences would not be in Madison,” Conroy says flatly. “We came here because the UW’s biochemistry program is one of the top in the country. It enabled us to hire really strong Ph.D. level scientists.”

Flash forward nine years: Exact Sciences has about 1,600 employees, 200 job vacancies, a stock market valuation of around $8 billion, and a fast-selling non-invasive colorectal cancer test called Cologuard. Other cancer tests are in the works.

Exact Sciences personifies the rise of the new Madison. It rides a wave of tech innovation that is closely tied to the UW’s fabled research prowess. But Cologuard was not tested at UW Hospital and Clinics, as you might expect, but at Mayo Clinics, which is Exact Sciences’ long-time partner. Exact’s other medical trials were conducted at MD Anderson Cancer Center in Houston.

Three years ago, when I wrote a mostly upbeat Isthmus cover story on technology transfer at UW-Madison, Conroy was a brooding presence. Doing clinical trials with the UW School of Medicine and Public Health was just too complicated, too prone for delay with the clinical trial review board, he complained. Both Anderson and Mayo were easier to work with “for a company operating at the speed of light.”

Conroy was heard. Exact Sciences is now doing preparatory research with the UW med school, but not yet a full-blown federally approved clinical trial.

Conroy sees progress. He considers himself a UW-Madison booster. But his impatience remains, and he’s definitely not alone in feeling the campus doesn’t yet have its act together on embracing the 21st century innovation economy. “C’mon, we can do better,” he says, sounding like a football coach at half-time.

To read more, please go here. And while you’re at it keep an eye out for other stories in the series.

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